Magnetic beads anonyanya kushandiswa mukudzivirira zvirwere, kuongorora ma molecular, kucheneswa kweprotein, kurongedza masero, nezvimwe minda.
Immunodiagnosis: Immunomagnetic beads inoumbwa nemagnetic particles uye zvinhu zvine anoshanda anoshanda mapoka. Mapuroteni ligands (maantigen kana masoja ekudzivirira chirwere) anobatanidzwa zvakabatana kumapoka anoshanda emagineti bead, uyezve immunoassay inoitwa pachishandiswa magnetic bead protein complexes.
Molecular diagnostic (nucleic acid extraction): Nanoscale magineti mabedhi ane mapoka epamusoro anogona adsorb nucleic acid anogona kupatsanurwa uye adsorbed nemagnetic field, uyezve eluted kuwana template nucleic acid.
Kucheneswa kweprotein: Muchinjikwa wakabatana agarose wakabatana pamwe nerecombinant fusion protein A/G pamusoro pemagineti beads, chaiyo inosunga mapuroteni eProteinA/G, uye pakupedzisira akakwenenzverwa kuwana masoja ekudzivirira chirwere.
Immune Diagnosis uye Molecular Diagnosis:
Imwe yeakakosha mashandisirwo emagineti mabedhi ari mukuongororwa kwekudzivirira, kwaave maturusi akakosha ekuona chirwere. Iyo yakasarudzika hunhu hwemagineti bead inomuka kubva mukugona kwavo kubata uye kupatsanura chaiwo maantigen kana masoja ekudzivirira chirwere kubva kuvarwere samples, kurerutsa maitiro ekuongorora. Nekubatana nekubatana maprotein ligands, senge maantigen kana masoja ekudzivirira chirwere, kumapoka anoshanda emagnetic beads, vaongorori vanogona kuita ma immunoassays nemazvo uye nekunyatso wedzera.Molecular diagnosis, imwe nzvimbo inofadza, inobatsira zvikuru kubva mukushandiswa kwemagnetic beads. Nemaitiro ekuongorora mamorekuru ari kuwana mukurumbira mumakore achangopfuura, magineti mabedhi anoita basa rakakosha mukuparadzanisa uye kubvisa nucleic acids, senge DNA kana RNA, kubva mubiological samples. Aya mabhero anoshanda seakasimba anotsigira, achifambisa kubatwa kwakanaka uye kucheneswa kwemamorekuru anonangwa. Iyi nzira yepamusoro yakaita kuti masayendisiti akwanise kuwana ruzivo rwakanyanya uye rwakavimbika, zvichiita kuti pave nemigumisiro iri nani yevarwere.
Kucheneswa kweProtein uye Kuronga Masero:
Magnetic beads anowanawo kushandiswa kwakanyanya mukucheneswa kweprotein, chiitiko chakakosha mukuvandudza zvinodhaka uye biochemistry research. Nekubatanidza matinji chaiwo kune mabehero, vaongorori vanogona kusarudza kusunga uye kubvisa mapuroteni anonangwa ane hutsanana hwakanyanya uye goho. Iyi nzira yekuchenesa inomhanyisa zvakanyanya maitiro ekutsvagisa, ichibvumira masayendisiti kuongorora uye kudzidza mapuroteni nenzira yakadzama.Kuronga masero, chikamu chakakosha chezvakasiyana-siyana zvekurapa nekutsvaga, chimwezve chikamu chakabatsirwa zvakanyanya nemagineti bead. Aya mabhero, akasanganiswa nemabiomarker kana masoja ekudzivirira chirwere, anofambisa kuparadzaniswa uye kurongeka kwemasero akasiyana. Nekushandisa magnetic field, masayendisiti anokwanisa kuronga nekuparadzanisa masero zvichienderana nemuviri uye kushanda kwawo. Kureruka uye kurongeka kwehunyanzvi uhu kwakasimbisa kuedza kwekutsvagisa mukunzwisisa maitiro akaomarara emasero, akadai sekufambira mberi kwegomarara uye mhinduro yekudzivirira muviri.
Nguva yekutumira: Jun-25-2023